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Weired location of points on MA plot?

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Weired location of points on MA plot?

ali_protocol
Dear all,

 I have a MA plot for "replicate" single channnel arrays, the loess curve is aligned to M=0. However,  I expect that M values be as close as possible to M=0 for replicate arrays, which is not the case. How may I obtain a measure that indicates the average distance of points to M=0?

Thanks indeed.
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