Dear All

I have a question about combining effect sizes generated by escalc in metafor. I realise these may be stupid things to do; but they are deliberately so to explain what I mean - I don't intend doing this!

I have 3 studies; each of which has a different measure of effect/presents the data differently, so I use escalc to calculate the effect size of each and combine them into a data-frame:

es1<-escalc(measure="MD", m1i=10 , m2i=5 , n1i=12 , n2i=12, sd1i=2, sd2i=2)

es2<-escalc(measure="RR", ai=10 , bi=5 , ci=12 , di=12)

es3<-escalc(measure="RR", ai=10 , ci=5 , n1i=15 , n2i=12)

es4<-rbind(es1, es2, es3) # combines the 3 effect sizes into a data frame

attach(es4) # makes the data frame available to R

es5<-rma(yi, vi, data=es4) # running the meta analysis here gives the error message

Error in rma(yi, vi, data = es4) :

Length of yi and ni vectors are not the same.

But if I save this as a .csv and open it in R using read.csv("E:/es5.csv", etc) i get a data frame that looks like this:

yi vi

1 5.0000 0.6667

2 0.6931 0.4667

3 0.4700 0.1500

I can run it using

rma(yi, vi, data=es4)

I have three questions.

1. Can escalc be used in this way to calculate each study effect size indvidually and then rbinding them into a data-frame (assuming that it is a sensible thing to do, which I realise the above probably isn't)?

2. What is the meaning of the error message:

Error in rma(yi, vi, data = es4) :

Length of yi and ni vectors are not the same.

3. Is it right to save it as a .csv, open it and re-run it as I have done?

Thanks very much, and to Wolfgang thanks for a great programme! I am using it in my MSc teaching here for healthcare students.

Edward

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